The U.S. biomedical research enterprise

Healing the NIH-Funded Biomedical Research Enterprise

Many feel that the R01 grant system supporting biomedical research in the U.S. is broken, discouraging entry of young investigators into the system and inadequately supporting more established investigators. Here, I argue for a "person-not-project"-based scheme that would permit creative, unfettered research by new investigators, better tie ongoing research contributions to continued funding, a...

US Biomedical Research under Siege

The stagnation of biomedical research funding in the US is placing great pressure on the research enterprise. It is time to consider some radical solutions.

Funding of US biomedical research, 2003-2008.

CONTEXT With the exception of the American Recovery and Reinvestment Act, funding support for biomedical research in the United States has slowed after a decade of doubling. However, the extent and scope of slowing are largely unknown. OBJECTIVE To quantify funding of biomedical research in the United States from 2003 to 2008. DESIGN Publicly available data were used to quantify funding fro...

Opinion: Addressing systemic problems in the biomedical research enterprise.

Last spring, the four of us published an essay in PNAS in which we described the severe problems now faced by scientists working in the US biomedical research system, recommending several steps that might be taken to improve the situation (1). As a follow up, we convened a two-day workshop in August that brought together 30 relatively senior individuals engaged in various aspects of biomedical ...

Elias A . Zerhouni Clinical Sciences US Biomedical Research : Basic , Translational